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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRKAA1 All Species: 34.24
Human Site: S476 Identified Species: 62.78
UniProt: Q13131 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13131 NP_006242.5 559 64009 S476 T Y L L D F R S I D D E I T E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001086285 574 65620 S491 T Y L L D F R S I D D E I T E
Dog Lupus familis XP_536491 563 64691 S480 T Y L L D F R S I D D E I T E
Cat Felis silvestris
Mouse Mus musculus Q5EG47 559 63911 S476 T Y L L D F R S I D D E I T E
Rat Rattus norvegicus P54645 559 63955 S476 T Y L L D F R S I D D E I T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506315 519 59478 E443 S I D D E I I E A K S G T T T
Chicken Gallus gallus Q9IA88 798 88848 S643 C I Y S S S G S S R E G R N L
Frog Xenopus laevis NP_001083882 560 64031 S477 T Y L L D F R S I D D E V T E
Zebra Danio Brachydanio rerio NP_001103756 573 65002 S470 T Y L L D F R S I D D D M M E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623371 515 58559 S441 W K I I N A Y S V R V R Q K N
Nematode Worm Caenorhab. elegans Q95ZQ4 626 70425 S535 S Y L L D F K S L A D E E S G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38997 535 61163 S459 C R W V P N S S A D G M L S N
Baker's Yeast Sacchar. cerevisiae P06782 633 72027 N557 Y D I G N K T N T N E K I P D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.2 92.5 N.A. 98.7 99.1 N.A. 89.2 27 88.7 84.4 N.A. N.A. 62.2 53.5 N.A.
Protein Similarity: 100 N.A. 97.3 93.7 N.A. 99.4 99.6 N.A. 91 43.1 94.6 90.9 N.A. N.A. 75.1 66.4 N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. 6.6 6.6 93.3 80 N.A. N.A. 6.6 53.3 N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 20 13.3 100 93.3 N.A. N.A. 33.3 80 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 45 33.4 N.A.
Protein Similarity: N.A. N.A. N.A. 62.4 51.9 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 0 0 16 8 0 0 0 0 0 % A
% Cys: 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 8 8 62 0 0 0 0 62 62 8 0 0 8 % D
% Glu: 0 0 0 0 8 0 0 8 0 0 16 54 8 0 54 % E
% Phe: 0 0 0 0 0 62 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 0 0 8 0 0 0 8 16 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 16 16 8 0 8 8 0 54 0 0 0 47 0 0 % I
% Lys: 0 8 0 0 0 8 8 0 0 8 0 8 0 8 0 % K
% Leu: 0 0 62 62 0 0 0 0 8 0 0 0 8 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 8 8 0 % M
% Asn: 0 0 0 0 16 8 0 8 0 8 0 0 0 8 16 % N
% Pro: 0 0 0 0 8 0 0 0 0 0 0 0 0 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Q
% Arg: 0 8 0 0 0 0 54 0 0 16 0 8 8 0 0 % R
% Ser: 16 0 0 8 8 8 8 85 8 0 8 0 0 16 0 % S
% Thr: 54 0 0 0 0 0 8 0 8 0 0 0 8 54 8 % T
% Val: 0 0 0 8 0 0 0 0 8 0 8 0 8 0 0 % V
% Trp: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 62 8 0 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _